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01-13-2011, 09:35 PM #5Senior Member
Just a hypothetical question
Originally Posted by StonedJustice
:wtf:
I call bullshit!
Effective bullshit requires more research.
Marinol1 (dronabinol) is the only US FDA-approved synthetic cannabinoid.
Always synthesized, never extracted.
"Stereospecific syntheses of THC and its analogs follow a general scheme, and this has been applied to the production of AJA (Scheme 1). In this procedure an alkylated resorcinol is condensed with an appropriate, chirally pure, terpene such as (+)-p-mentha-2,8-diene-1-ol (2), cis-chrysanthenol (5), cis-verbinol (6), or (+)-trans-2-carene oxide (7). The substituted resorcinol portion of the molecule is made by the reaction of 1,6-dimethoxyphenol with 1,1-dimethylheptanol in the presence of methane sulfonic acid. The product is then esterified with diethyl phosphite and triethylamine with cooling to yield the diethyl phosphate derivative. Reduction with lithium in liquid ammonia produces 1-(1′,1′-dimethylheptyl) 3,5-dimethoxybenzene (1) that is used in the next step. This involves a condensation of the p-mentha-2,8-diene-1-ol (2) shown in Scheme 1 with dimethylheptyl resorcinol (1) catalyzed by p-toluenesulfonic acid to give the dimethylheptyl analog of Δ8 â??THC. Following conversion of the cannabinoid to the acetate (3), the allylic methyl group is oxidized to an aldehyde using selenium dioxide. Further oxidation to a carboxylic acid is accomplished by the use of sodium chlorite. Finally, free AJA (4) is obtained by saponification of the acetyl group with sodium carbonate in aqueous methanol.
"
Not faulting commercial croppers here.
Somebody has to do it.
And it require knowledge, skills, and stones.:thumbsup:
But, you are asking people to spoon-feed you while they aid and abet a federal felony under false pretenses.
Suggest that you read more, learn more, and in short, do the work yourself!
And, please do it honestly, and elsewhere.
Mahalo and good luck.
Weezard
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