Creatine is not what they test for, it is creatinine- a waste product found in the urine. Creatinine takes at least a day and a half to metabolize from creatine, usually three days.

Drinking the detox drink the day of will do you no good because it will just dilute your urine w/o adding the necessary creatinine in time (vitamin b goes through you like a bullet though). Drinking the detox drink a few days before is also no good because it won't dilute your urine. Just to clarify; Detox drinks won't do you any good. If this is a pre-employment test I would recommend substituting, and if it is court ordered you need to go get creatine supplements TODAY and read the sticky on dilution.

But let me tell you as a biochem major, detox drinks are a waste of money.