More info needed.

What is the size of your room (W x L x H)?
How many plants?
What is the CFM of the fan?
What is the diameter of the duct?
What is the size of the intake port?
Passive or active intake?
How long is the duct work and how many 90 degree elbows?
Where does the fan exhaust (if interior exhaust, describe)?
What is the size of the can filter?

If you dial these factor in correctly you should not have an issue. A little ONA should take care of any residual odor. If this is a critical factor and you still can't manage to contain the odor then you could consider a tent, although that should not be needed if you get the above factors matched up.