This is one of those subjects people tend to disagree on.

I've read a few threads where people swore their potency had dropped after a few runs.

However, I've seen FAR more grows where a person cloned off the plants about to go into the flower room over and over for years without any issues.

I'd say it's not likely to be a big problem though. If your concerned, keep a bonsai mom. :thumbsup: