Quote Originally Posted by PufferLungs
Also, mixing marijuana with prescription medication for your depression is not a good idea. MAOI or other reuptake inhibitors change your brain chemistry.
Irreversible maoi's, like tranylcypromine (Parnate), haven't been widely prescribed for more than 20 years due to their many side effects and conflicts with common foods. Only moclobemide is really active in the market place from that group and it's a reversable maoi, so not dietary restrictions and no noted interaction with cannabis. The reuptake inhibitors work selectively on serotonin (hence ssri, selective serotonin reuptake inhibitor). All they do is lengthen the period of time your neural synapses are exposed to serotonin by preventing reabsorption for a while longer than usual. Cannabis has a modulating effect on neurotransmitters, so, theoretically speaking cannabis might possibly work at crossed purposes with ssri medications, but there is no current data to either support or deny the idea.

Strange neurological symptoms should always be checked out, if you're feeling weird smoking do seek medical advice.