i used to do about 500-600 milligrams and i would get so fucked that i wouldnt feel any pain. i could jump off of a picnic table and land face first and not feel it....until the next morning. lol DXM will definitely get you as high or higher than most drugs. be careful though!!!!!!!! do not, i repeat do not! overdose, or do this while you are on antidepressants.....300mg would be enough for a first timer.be careful.