5/500 you don't need to worry about taking too many because of the opiate(5) but the Tylenol(500) could possibly hurt your stomach. To be safe it is probably a good idea to check out a bottle of Tylenol for their recommended max per/day dosage or search it out on the web. Ok, that's my disclaimer. Now I would take at least 3, chew them up or disolve in water. And drink a beer/drink or two. The alcohol will seriously kick in the opiate and make it all warm and fuzzy. If you start itching you have plenty in your system, just scratch yourself and enjoy the wonderful relief. That is just my personal preference. But seriosly at that dosage the Tylenol is the limiting factor as to how many you can take. Just don't eat them all and run out, leaving yourself nothing for the pain. I hope you feel better.