all really depends.are u on a time schedule, do u have a certin limit of plants u are allowerd to have based on state and county ordinanaces? if your looking 2 get started up and running as fast as possible,i would say fem seeds.this is what i have resorted 2,i usually start from clone only no mothers.well things have changed.i have 9 fem seeds going that i intend to use as mother plants and clone from them.by starting with seeds u allready know are female it saves u the time of taking cuttings and then flowering them 2 see what sex they are.especially if space is an issue.if u want moms i would say go fem.if u dont really care and have tons of space and dont mind wasting supplies for something your going to chop down,go for it....the only real upside that i see is this. one,some strains are not avail femmed and there are some badass strains out there. two,if u want to start breeding your own strains.this is all my personal opinion though.im sure others differ but thats just me.