Quote Originally Posted by denialisback
not quite, the study is saying that in the mice that were pre-treated there was a lower immunoreaction - i.e. the brain protects itself less..

Thus indicating long term exposure to THC decreases the neurological immuno ability of mice to supress the THC from affecting memory..

Quite an interesting study indeed. I would have expected the opposite too thcbongman :-)


Odd.

Peace,
denial
It's actually states the opposite.

Zif268 immunoreactivity was reduced in the CA3 of the hippocampus and in the prefrontal cortex only in non-pretreated animals, indicating that although tolerance to the effects of THC on neuronal activity was evident, cannabinoid-induced memory impairment in these animals persisted even after 24 days of exposure.
Which is why I don't understand the conclusion:

This study shows that after extended administration of THC, its spatial memory-impairing effects are resistant to tolerance.