Results 1 to 10 of 53
Threaded View
-
03-04-2010, 03:52 AM #35
Junior Member
DOT P test
Originally Posted by Burnt Toast
Nitrites can be readily detected by a urinalysis dipstick test or through direct chemical analysis. Because nitrites do not interfere with immunoassays, samples containing concentrations of THC above the threshold will be routinely assayed for the THC-COOH metabolite by GC/MS. A urine sample that exhibits little or no recovery of a deuterated IS or target drug is highly suggestive of an adulterant such as nitrite (2).
Using elemental analysis, mass spectrometry (for pyridine), ion chromatography (for chloride), and inductively coupled plasma atomic emission spectroscopy, the active ingredient in Urine Luck was determined to be PCC. Urine samples adulterated with PCC tested by GC/MS will produce results that are similar to those for nitrite, i.e., low or no recovery of the IS or target drug. This adulterant differs from nitrite, however, because at high concentrations, the chemical also produces negative immunoassay screening results. Thus, drug testing laboratories unaware of the presence of PCC will not perform GC/MS analysis, and the use of PCC may escape detection. Its presence can be suspected by the presence of an abnormally low pH or the appearance of an orange tint to the urine.
So basically if you can get through without a GC/MS run you may be ok. If not, this stuff will destroy the internal standard which sets off a red flag that the sample may contain an adulterant. An inexperienced GC/MS operator could misinterpret results like this but I have a feeling someone more experienced would have to sign off on it and thus, would recognize.
Nothing says friendship like borrowed urine
References:
(1)Alan H.B. Wu,a, Ben Bristol, Karen Sexton, Gina Cassella-McLane, Verena Holtman and Dennis W. Hill. "Adulteration of Urine by "Urine Luck" Clinical Chemistry 45: 1051-1057, 1999;
(2)ElSohly MA, Feng S, Kopycki WJ, Murphy TP, Jones AB, Davis A, Carr D. A procedure to overcome interferences caused by the adulterant "Klear" in the GC-MS analysis of 11-nor-9-THC-9COOH. J Anal Toxicol 1997;21:240-242
Similar Threads
-
PASSED AT HOME DRUG TEST WILL I PASS LAB TEST?! OPINIONS NEEDED
By eillim in forum Drug TestingReplies: 5Last Post: 07-21-2013, 01:51 AM -
Lab Corp Urine test I toked a few hits 25 days ago I have pre-employment test
By gotago1 in forum Drug TestingReplies: 1Last Post: 06-22-2011, 12:08 AM -
Does weed quality affect drug test? I'm way scared :( Test tomorrow
By Rainbow Brite in forum Drug TestingReplies: 5Last Post: 05-18-2011, 09:24 PM -
Drug Test Curiosity? Home Test Vs. Lab Test
By mr.squonk in forum Drug TestingReplies: 6Last Post: 02-13-2011, 10:20 PM -
Took home test & LabCorp test, haven't heard back - Am I Good?
By BigKnixFan in forum Drug TestingReplies: 3Last Post: 05-10-2008, 02:06 PM










Register To Reply
Staff Online