hmmm, interesting concept.
i'm no expert on this board, but, my 2 cents...

reducing root mass in theory might be ok, as long as the roots you do have are able to get the volume of nutrients the plant needs.

but, i just dont see how a miniature plant could possibly have any real substantial yield. there just couldnt be the multitudes of bud sites that a standard bushy plant would produce.
but, on the other hand, if your goal is to just create a unique houseplant, of a variety you have a particular affection for, that might work.

one other thought. u may stress the hell outta it and it hermie, if so, watch out for your girls.

just thinkin out loud.