Grow a plant as a mother. Leave her under 24 hour light, often just flourecents. Then on a regular basis take a bunch of clones. I have no difficulty taking a dozen a month; a large mother to fill a larger grow space could give 60 from what others have said.

It's my goal to have 3-4 mothers of different flavors currently I have a "church", and "power plant", however I had a freeze in January and lost much as far as veg, generations

What I've read is you could keep the same mother for 5-7 years, some strains long as 15 years. If you read the bonsai thread, that guy is genius and cuts the roots down to an 8x8 soil container and small plant. He's got all the info you want on that post...which I'm too lazy to find the link to , but it's under advanced techniques.