I've gotten the chills here and there and it usually lasts for about 5 or 10 minutes. Oddly enough last night I smoked and got pretty lit up (it was from one of my plants that has been curing for awhile and had some pretty good sized buds) and I had the chills for like an hour-I was shivering in my house!!!! A woman who was over and smoked with me didn't get that effect at all.