Three or four colchicine? I WISH! I've had multiple gout flare-ups - the kind where the sheet catching your toe nail in the night wakes you in a cold sweat screaming. My doc's always told me to take two at first, then one every hour until I feel sick to my stomach. The bottle even says "until you vomit.."

On average, I take them for 15 hours and drink as much water as I can stand. Seventeen pills by .6 mg each runs to be 10.2 mg, and I've had to take this dose at least 10 times in the past three years. I imagine my body (6', 165 lbs) could easily withstand 20 mg in a day.

I understand the quality of genetics has improved vastly, but there's always room for science! Right?!

Besides, colchicine can't replicate! The smallest dose of it in the soil wouldn't metabolize through the fruiting phase, anyway.

Keep up the great work y'all! Wish I was there with ya!