100% female plants, seedlings treated wColchicine

[infogift1967]

Colchicine is a drug. It, like any other drug or substance can be toxic depending on the dose. Even tap water is toxic if you ingest enough at one time.

Since a gout patient takes three or 4 pills (0.6mg ) the theraputic dose is 1.8 to 2.4 mg in a single day. This is direct oral ingestion.

Contrast that with a single pill (0.6mg), a fraction of which is applied to several seedlings and then exposed to intense light for some months, which completely degrades the original alkaloid.

But to be fair, the most realistic hazard would be to carelessly handle
the colchicine when applying it to the seedlings. You wouldn't want to wet your fingers with it, and wipe your eyes for example. But then I wouldn't want to get fertilizer or beer in my eyes. It all comes down to common sense.

[Rusty Trichome]

Are you by chance an MD? If not, I would like to request you stop giving blanket medical evaluations and drug safety advise. For some, it quite possibly could be, at the very least...harmful. I understand the dilutions argument, but you still have no clue as the safety for those on a regimented drug schedule for treatments of shitloads of diseases or conditions. "Because the guy's at the other site said it was ok" is not a valid argument.

Colchicine (Colchicine) Drug Information: Uses, Side Effects, Drug Interactions and Warnings at RxList

"Adverse reactions in decreasing order of severity are: bone marrow depression, with aplastic anemia, with agranulocytosis or with thrombocytopenia may occur in patients receiving long-term therapy. Peripheral neuritis, purpura, myopathy, loss of hair, and reversible azoospermia have also been reported.

Vomiting, diarrhea, and nausea may occur with colchicine therapy, especially when maximal doses are necessary for a therapeutic effect. To avoid more serious toxicity, the drug should be discontinued when these symptoms appear, regardless of whether or not joint pain has been relieved.

Dermatoses have been reported. Hypersensitivity reactions may occur infrequently."

Drug Interactions:
Colchicine is inhibited by acidifying agents. The action of colchicine is potentiated by alkalinizing agents.

Colchicine may increase sensitivity to the CNS* depressants.

Response to sympathomimetic agents' may be enhanced by colchicine.


*CNS stands for central nervous system.

Doubtful 95% (random number) of us would have a problem. But you are willing to risk it for the remainder of the group...?

I would like to take this opportunity to extend this warning to products like gibberellic acid, hormones, steroids. Know what you're using, as it may affect you adversely.

[carinia]

Being a woman, anything that affects your chromosones at birth (Or germination ) makes me think about flipper babies.

I dont want flipper babies.

[wraithe]

this may just be me, but i think a fact has been overlooked. Most "medical marijuana" users take other prescription drugs. I could see this drug interacting with other drugs they are taking causing serious harm

[rudy2010]

I believe someone mentioned the key thing. You have to grow the seeds that were a result of the plants being treated with the colchicine and get seeds from those plants but you CANNOT smoke those plants from the first generation of colchicine treated seeds. Just second and subsequent generations. Also as mentioned they will then be polyploid but I have not heard of colchicine causing the seeds to be female. If the seeds result in all female plants you would have to get another male somewhere to create the second and subsequent generations that you can smoke.

Has anyone heard of any negative effects from the second generation seeds. Any information on whether there is any colchocine in the subsequent generations.

[Hazebound]

Colchicine treated plants are sterile and must be cloned.

[the image reaper]

a reminder: Colchicine is a hazardous, dangerous, substance ... DO NOT USE COLCHICINE ! ... there are many ways to grow superior plants, with no risk, learn them, use them ... this whole 'feminized' fad blows, anyway :wtf: ... grow out your plants, from 'regular' seeds, select your best females, and clone them :thumbsup:... :smokin:

[rudy2010]

... grow out your plants, from 'regular' seeds, select your best females, and clone them

True that. The quality is soooo good and available now adays that messing with marginal and difficult chemicals is a very bad idea.:smokin:

[MimbresValley]

interesting,infogift1967

[NoDrugs4Me]

Three or four colchicine? I WISH! I've had multiple gout flare-ups - the kind where the sheet catching your toe nail in the night wakes you in a cold sweat screaming. My doc's always told me to take two at first, then one every hour until I feel sick to my stomach. The bottle even says "until you vomit.."

On average, I take them for 15 hours and drink as much water as I can stand. Seventeen pills by .6 mg each runs to be 10.2 mg, and I've had to take this dose at least 10 times in the past three years. I imagine my body (6', 165 lbs) could easily withstand 20 mg in a day.

I understand the quality of genetics has improved vastly, but there's always room for science! Right?!

Besides, colchicine can't replicate! The smallest dose of it in the soil wouldn't metabolize through the fruiting phase, anyway.

Keep up the great work y'all! Wish I was there with ya!