PRIONS

Cannabidiol Prevents Prion Accumulation and Protects Neurons against Prion Toxicity
Nonpsychoactive Cannabidiol Prevents Prion Accumulation and Protects Neurons against Prion Toxicity -- Dirikoc et al. 27 (36): 9537 -- Journal of Neuroscience

Cannabidiol May be Effective in Preventing Bovine Spongiforme Enzephalopathy (Mad Cow Disease)
BBSNews - Marijuana Ingredient May Prevent Mad Cow Disease




PRURITIS

Cream with endocannabinoids effective in the treatment of pruritus
BBSNews: Science: Cream with endocannabinoids effective in the treatment of pruritus due to kidney disease

Topical cannabinoid agonists : An effective new possibility for treating chronic pruritus.
Clinical Studies and Case Reports

Dronabinol in patients with intractable pruritus secondary to cholestatic liver disease.
Clinical Studies and Case Reports




SAFETY

Proven: Cannabis is safe medicine
Proven: Cannabis is safe medicine

Excerpt from the Merck Manual
Excerpt from the Merck Manual

Medical use of cannabinoids does not cause an increase in serious adverse health effects
The adverse effects of cannabinoids: implications for use of medical marijuana -- Degenhardt and Hall 178 (13): 1685 -- Canadian Medical Association Journal

Claims Linking Health Problems And The Strength Of Cannabis May Be Exaggerated
Claims Linking Health Problems And The Strength Of Cannabis May Be Exaggerated





SATIVEX

Sativex in the treatment of pain caused by rheumatoid arthritis
Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis -- Blake et al. 45 (1): 50 -- Rheumatology

Sativex produced significant improvements in a subjective measure of spasticity
Clinical Studies and Case Reports

Sativex in patients suffering from multiple sclerosis
Clinical Studies and Case Reports

Sativex in patients suffering from multiple sclerosis associated detrusor overactivity
Clinical Studies and Case Reports

Sativex showed positive effects in 65 per cent of patients with chronic diseases
IACM-Bulletin

Cannabis; adverse effects from an oromucosal spray.
http://marijuana.researchtoday.net/archive/4/8/1357.htm

Cannabis, pain, and sleep: lessons from trials of Sativex, a cannabis-based medicine.
Cannabis, pain, and sleep: lessons from therapeutic clinical trials of Sativex, a cannabis-based medicine.

Sativex successfully treats neuropathic pain characterised by allodynia
ScienceDirect - Pain : Sativex successfully treats neuropathic pain characterised by allodynia: A randomised, double-blind, placebo-controlled clinical trial




SCHIZOPHRENIA/ MENTAL DISORDERS

Increased cannabinoid receptor density in the posterior cingulate cortex in schizophrenia.
(may need free registration)
Log In Problems

Symptoms of schizotypy precede cannabis use.
UKCIA forum :: Research :: Symptoms of schizotypy precede cannabis use.

Cannabidiol as an antipsychotic
Clinical Studies and Case Reports

Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients
Unbound MEDLINE | Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients: Impact of cannabis use. Journal article

Delta-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition
Unbound MEDLINE | An Experimental Study of Catechol-O-Methyltransferase Val(158)Met Moderation of Delta-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition. Journal article

Cannabis is a First-Line Treatment for Childhood Mental Disorders
Dr. Tod Mikuriya: Cannabis as a Frontline Treatment for Childhood Mental Disorders

Cannabis does not induce schizophrenia,
Cannabis does not induce schizophrenia, Dutch scientists say

Cannabis use does not cause schizophrenia
Cannabis use does not cause schizophrenia

Cannabinoids and psychosis.
Cannabinoids and psychosis. [Int Rev Neurobiol. 2007] - PubMed Result

Cannabis as a psychotropic medication
Cannabis as a psychotropic medication -- Chaturvedi 185 (1): 78 -- The British Journal of Psychiatry

Study Shows Long Term Marijuana Users Healthy
Erowid Cannabis Vault : Health Effects : Study #3

Cannabis and schizophrenia link blurs further
Cannabis and schizophrenia link blurs further - health - 16 April 2005 - New Scientist

Evidence does not show a strong causal relation between the use of cannabis and psychosocial harm
NLH - Mental Health - Aetiology - Review: current evidence does not show a strong causal relation between the use of cannabis in young people and psychosocial harm

No Increased Schizophrenia Risk With Use Of Cannabis
No Increased Schizophrenia Risk With Use Of Cannabis: The Hempire - [cannabis, legalise]




SICKLE CELL DISEASE

Sickle Cell Disease and Cannabis
AAMC: Those who suffer from sickle-cell disease experience painful episodes or attacks

Marijuana smoking in young adults with sickle cell
http://caribbean.scielo.org/scielo.p...lng=en&nrm=iso

Medical use of cannabis in sickle cell disease
Medical use of cannabis in sickle cell disease - Current medical events - Hemp and Medicine - Benvenuti su www.Chanvre-info.ch! Lo specialista dellla canapa (Cannabis) in Svizzera.

Cannabis use in sickle cell disease: a questionnaire study.
Cannabis use in sickle cell disease: a questionnai...[Br J Haematol. 2005] - PubMed Result



SLEEP MODULATION

Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats. (may need free registration)
Log In Problems

Dronabinol reduces signs and symptoms of idiopathic intracranial hypertension
Clinical Studies and Case Reports

Cannabis-based medicine in central pain in multiple sclerosis.
Clinical Studies and Case Reports

Two cannabis based medicinal extracts for relief of central neuropathic pain
Clinical Studies and Case Reports

Functional role for cannabinoids in respiratory stability during sleep
AAMC: Functional role for cannabinoids in respiratory stability during sleep

THC reduces sleep apnoea in animal research
IACM-Bulletin

Cannabis, pain, and sleep: lessons from trials of Sativex, a cannabis-based medicine.
Cannabis, pain, and sleep: lessons from therapeutic clinical trials of Sativex, a cannabis-based medicine.

Dronabinol and marijuana in HIV-positive marijuana smokers. Caloric intake, mood, and sleep.
Dronabinol and marijuana in HIV-positive marijuana smokers. Caloric intake, mood, and sleep.

Effect of illicit recreational drugs upon sleep: Cocaine, ecstasy and marijuana.
Effect of illicit recreational drugs upon sleep: Cocaine, ecstasy and marijuana.





SOCIAL ADJUSTMENT

Some go without a cigarette: characteristics of cannabis users who have never smoked tobacco.
Some go without a cigarette: characteristics of cannabis users who have never smoked tobacco.

Marijuana use motives and social anxiety among marijuana-using young adults.
Marijuana use motives and social anxiety among marijuana-using young adults.





SPASTICITY

The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury.
Clinical Studies and Case Reports

Cannabis-based medicine in spasticity caused by multiple sclerosis
Clinical Studies and Case Reports

Cannabinoids in multiple sclerosis
Clinical Studies and Case Reports

Sativex produced significant improvements in a subjective measure of spasticity
Clinical Studies and Case Reports

Do cannabis-based medicinal extracts have general or specific effects on symptoms in ms?
Clinical Studies and Case Reports

Efficacy, safety and tolerability of an oral cannabis extract in the treatment of spasticity
Clinical Studies and Case Reports

Are oral cannabinoids safe and effective in refractory neuropathic pain?
Clinical Studies and Case Reports

Experiences with THC-treatment in children and adolescents
Clinical Studies and Case Reports

The treatment of spasticity with D9-THC in patients with spinal cord injury
Clinical Studies and Case Reports

The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity
Clinical Studies and Case Reports

Nabilone in the treatment of multiple sclerosis.
Clinical Studies and Case Reports

Treatment of spasticity in spinal cord injury with dronabinol
Clinical Studies and Case Reports

Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects
Clinical Studies and Case Reports

Effect of cannabinoids on spasticity and ataxia in multiple sclerosis.
Clinical Studies and Case Reports

Delta-9-THC in the treatment of spasticity associated with multiple sclerosis.
Clinical Studies and Case Reports

Effect of Delta-9-THC on EMG Measurements in Human Spasticity
Clinical Studies and Case Reports

The effect of delta-9-THC on human spasticity.
Clinical Studies and Case Reports

Cannabis effect on spasticity in spinal cord injury.
Clinical Studies and Case Reports

Treatment of human spasticity with delta 9-tetrahydrocannabinol.
` Clinical Studies and Case Reports

Marihuana as a therapeutic agent for muscle spasm or spasticity.
Clinical Studies and Case Reports

The perceived effects of marijuana on spinal cord injured males.
Clinical Studies and Case Reports

Motor effects of delta 9 THC in cerebellar Lurcher mutant mice.
Unbound MEDLINE | Motor effects of delta 9 THC in cerebellar Lurcher mutant mice. Journal article

Cannabis-based medicine in spasticity caused by multiple sclerosis
Unbound MEDLINE | Randomized controlled trial of cannabis-based medicine in spasticity caused by multiple sclerosis. Journal article

Nabilone significantly reduces spasticity-related pain
Unbound MEDLINE | Low dose treatment with the synthetic cannabinoid Nabilone significantly reduces spasticity-related pain : A double-blind placebo-controlled cross-over trial. Journal article





SPINAL CORD INJURY

The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury.
Clinical Studies and Case Reports

Are oral cannabinoids safe and effective in refractory neuropathic pain?
Clinical Studies and Case Reports

The treatment of spasticity with D9-THC in patients with spinal cord injury
Clinical Studies and Case Reports

Delta-9-THC as an alternative therapy for overactive bladders in spinal cord injury
Clinical Studies and Case Reports

The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity
Clinical Studies and Case Reports

Treatment of spasticity in spinal cord injury with dronabinol
Clinical Studies and Case Reports

Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects
Clinical Studies and Case Reports

The effect of delta-9-THC on human spasticity.
Clinical Studies and Case Reports

Cannabis effect on spasticity in spinal cord injury.
Clinical Studies and Case Reports

Marihuana as a therapeutic agent for muscle spasm or spasticity.
Clinical Studies and Case Reports

The perceived effects of marijuana on spinal cord injured males.
Clinical Studies and Case Reports




STROKE

Cannabidiol has a cerebroprotective action
Unbound MEDLINE | Delayed treatment with cannabidiol has a cerebroprotective action via a cannabinoid receptor-independent myeloperoxidase-inhibiting mechanism. Journal article

Delta(9)-THC) prevents cerebral infarction
Unbound MEDLINE | Delta(9)-tetrahydrocannabinol (Delta(9)-THC) prevents cerebral infarction via hypothalamic-independent hypothermia. Journal article

Medical marijuana: study shows that THC slows atherosclerosis
The Next Hurrah: Medical marijuana: study shows that THC slows atherosclerosis

US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants
Cannabinoids as antioxidants and neuroprotectants - US Patent 6630507





TEA AS MEDICINE

Cannabis tea revisited: A systematic evaluation
Cannabis tea revisited: a systematic evaluation of...[J Ethnopharmacol. 2007] - PubMed Result

Cuppa Gives A Better 'ooh'
Cuppa Gives A Better 'ooh': The Hempire - [cannabis, uk]

With the use of cannabis tea only a small proportion of THC in the cannabis is ingested
Internationale Arbeitsgemeinschaft Cannabis als Medizin




THC/ TETRAHYDROCANNABINOL

THC is effective in the treatment of tics in Tourette syndrome
Clinical Studies and Case Reports

THC effective in Tourette-Syndrome
AAMC: THC effective in Tourette-Syndrome

THC effective in Tourette syndrome in a 6-week trial
IACM-Bulletin

Treatment of Tourette's Syndrome With Delta-9-Tetrahydrocannabinol
Treatment of Tourette's Syndrome With Delta-9-Tetrahydrocannabinol -- M?LLER-VAHL et al. 156 (3): 495 -- Am J Psychiatry

THC inhibits primary marker of Alzheimer's disease
IACM-Bulletin

THC improves appetite and reverses weight loss in AIDS patients
Clinical Studies and Case Reports

Cancer-related anorexia-cachexia syndrome
Unbound MEDLINE | Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled clinical

THC effective in appetite and weight loss in severe lung disease (COPD)
IACM-Bulletin

The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat
Unbound MEDLINE | The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat involves the CB(2) cannabinoid receptor. Journal article

Synergy between Delta(9)-tetrahydrocannabinol and morphine in the arthritic rat
Unbound MEDLINE | Synergy between Delta(9)-tetrahydrocannabinol and morphine in the arthritic rat. Journal article

Bronchial effects of aerosolized delta 9-tetrahydrocannabinol
Clinical Studies and Case Reports

Bronchodilator effect of delta1-tetrahydrocannabinol administered by aerosol
Clinical Studies and Case Reports

Effects of smoked marijuana in experimentally induced asthma.
Clinical Studies and Case Reports

Marijuana and oral delta9-tetrahydrocannabinol on specific airway conductance
Clinical Studies and Case Reports

New Synthetic Delta-9-THC Inhaler Offers Safe, Rapid Delivery
New Synthetic Delta-9-THC Inhaler Offers Safe, Rapid Delivery, Phase I Study

Smoked marijuana and oral delta-9-THC on specific airway conductance in asthmatic subjects
Acute effects of smoked marijuana and oral delta-9-tetrahydrocannabinol on specific airway conductance in asthmatic subjects

Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme.
Clinical Studies and Case Reports

9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer
{Delta}9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer Cells through Cdc2 Regulation -- Caffarel et al. 66 (13): 6615 -- Cancer Research

THC and prochlorperazine effective in reducing vomiting in women following breast surgery
IACM-Bulletin

{Delta}9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T Cells
{Delta}9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T Cells Is Regulated by Translocation of Bad to Mitochondria -- Jia et al. 4 (8): 549 -- Molecular Cancer Research

Delta(9)-THC) prevents cerebral infarction
Unbound MEDLINE | Delta(9)-tetrahydrocannabinol (Delta(9)-THC) prevents cerebral infarction via hypothalamic-independent hypothermia. Journal article

Medical marijuana: study shows that THC slows atherosclerosis
The Next Hurrah: Medical marijuana: study shows that THC slows atherosclerosis

Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects
Clinical Studies and Case Reports

The effect of delta-9-THC on human spasticity.
Clinical Studies and Case Reports

The treatment of spasticity with D9-THC) in patients with spinal cord injury
Clinical Studies and Case Reports

Delta-9-THC as an alternative therapy for overactive bladders in spinal cord injury
Clinical Studies and Case Reports

The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity
Clinical Studies and Case Reports

The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury.
Clinical Studies and Case Reports

Delta-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition
Unbound MEDLINE | An Experimental Study of Catechol-O-Methyltransferase Val(158)Met Moderation of Delta-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition. Journal article

The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity
Clinical Studies and Case Reports

Marihuana as a therapeutic agent for muscle spasm or spasticity.
Clinical Studies and Case Reports

Analgesic effect of delta-9-tetrahydrocannabinol.
Clinical Studies and Case Reports

The analgesic properties of delta-9-tetrahydrocannabinol and codeine.
Clinical Studies and Case Reports

The perceived effects of smoked cannabis on patients with multiple sclerosis.
Clinical Studies and Case Reports

Cannabis use for chronic non-cancer pain
Clinical Studies and Case Reports

Tetrahydrocannabinol for treatment of chronic pain
Clinical Studies and Case Reports

Delta-9-THC based monotherapy in fibromyalgia patients
Clinical Studies and Case Reports

Delta(9)-THC) prevents cerebral infarction
Unbound MEDLINE | Delta(9)-tetrahydrocannabinol (Delta(9)-THC) prevents cerebral infarction via hypothalamic-independent hypothermia. Journal article

Delta(9)-Tetrahydrocannabinol protects hippocampal neurons from excitotoxicity
Unbound MEDLINE | Delta(9)-Tetrahydrocannabinol protects hippocampal neurons from excitotoxicity. Journal article

THC effective in intractable nausea in a patient undergoing gastric bypass surgery
BBSNews - Oral THC Eased Gastric Bypass Nausea

Differential Effects of THC or CBD-rich Cannabis Extracts on Working Memory in Rats
http://www.ukcia.org/research/THCCBDWorkingMemory.pdf

Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy
Report on New Mexico Cancer/Marijuana Study

Delta-9-Tetrahydrocannibinol as an Antiemetic in Cancer Patients Receiving High-Dose Methotrexate
Inhaled THC Produces Better Blood Levels than THC by Mouth

Enhancing the in vitro cytotoxic activity of Delta(9)-THC in leukemic cells through a combinatorial approach.
Enhancing the in vitro cytotoxic activity of Delta(9)-tetrahydrocannabinol in leukemic cells through a combinatorial approach.




THC ACID/ THCA

Production of THC acid by the biosynthetic enzyme secreted from transgenic Pichia pastoris.
Production of Delta(1)-tetrahydrocannabinolic acid by the biosynthetic enzyme secreted from transgenic Pichia pastoris.



TOBACCO VS CANNABIS

Cannabis Smoke and Cancer: Assessing the Risk
Cannabis Smoke and Cancer: Assessing the Risk - NORML

Cannabis and tobacco smoke are not equally carcinogenic
Cannabis and tobacco smoke are not equally carcinogenic

Smoking Marijuana Does Not Cause Lung Cancer
US: Web: Study: Smoking Marijuana Does Not Cause Lung Cancer

Tobacco and marijuana use on offspring growth from birth through 3 years of age.
The effects of prenatal tobacco and marijuana use ...[Neurotoxicol Teratol. 1992 Nov-Dec] - PubMed Result

Progression from marijuana use to daily smoking and nicotine dependence
Erowid.org: Erowid Reference 6951 : Progression from marijuana use to daily smoking and nicotine dependence in a national sample of U.S. adolescents : Timberlake DS, Haberstick BC, Hopfer CJ, Bricker J, Sakai JT, Lessem JM, Hewitt JK

High anxieties - What the WHO doesn't want you to know about cannabis
High anxieties - What the WHO doesn't want you to know about cannabis - 21 February 1998 - New Scientist

Radioactive tobacco
Radioactive tobacco

Some go without a cigarette: characteristics of cannabis users who have never smoked tobacco.
Some go without a cigarette: characteristics of cannabis users who have never smoked tobacco.

Cannabis use when it's legal
ScienceDirect - Addictive Behaviors : Cannabis use when it's legal

Aluminum in Tobacco and Cannabis and Smoking-Related Disease
ScienceDirect - The American Journal of Medicine : Aluminum in Tobacco and Cannabis and Smoking-Related Disease




TOLERANCE

A Molecular Basis of Analgesic Tolerance to Cannabinoids
A Molecular Basis of Analgesic Tolerance to Cannabinoids -- Tappe-Theodor et al. 27 (15): 4165 -- Journal of Neuroscience




TOURETTE'S SYNDROME

Treatment of Tourette's Syndrome With Delta-9-Tetrahydrocannabinol
Treatment of Tourette's Syndrome With Delta-9-Tetrahydrocannabinol -- M?LLER-VAHL et al. 156 (3): 495 -- Am J Psychiatry

THC is effective in the treatment of tics in Tourette syndrome
Clinical Studies and Case Reports

Treatment of Tourette's syndrome with Delta 9-tetrahydrocannabinol
Clinical Studies and Case Reports

Cannabinoids: possible role in patho-physiology and therapy of Gilles de la Tourette syndrome.
Clinical Studies and Case Reports

THC effective in Tourette-Syndrome
AAMC: THC effective in Tourette-Syndrome

THC effective in Tourette syndrome in a 6-week trial
IACM-Bulletin

Cannabinoids reduce symptoms of Tourette's syndrome.
Cannabinoids reduce symptoms of Tourette's syndrom...[Expert Opin Pharmacother. 2003] - PubMed Result




VAPORIZERS

Vaporization as a smokeless cannabis delivery system
Clinical Studies and Case Reports

Smokeless Cannabis Delivery Device Efficient And Less Toxic
Smokeless Cannabis Delivery Device Efficient And Less Toxic

Volcano is to Vaporizer As Porsche is to Automobile
CCRMG

Recommendation to Patients: "Don??t smoke, Vaporize"
CCRMG

Decreased respiratory symptoms in cannabis users who vaporize.
Decreased respiratory symptoms in cannabis users who vaporize.

Use of vaporizers reduces toxins from cannabis smoke
IACM-Bulletin

Marijuana Water Pipe and Vaporizer Study
Marijuana Water Pipe and Vaporizer Study




WILSON'S DISEASE

Cannabis sativa and dystonia secondary to Wilson's disease. (may need free registration)
Log In Problems



WITHDRAWAL SYNDROME

Comparison of symptoms during abstinence from cannabis, tobacco, and both substances
http://marijuana.researchtoday.net/archive/4/7/1349.htm .

Excerpt from the Merck Manual
Excerpt from the Merck Manual

Effect of illicit recreational drugs upon sleep: Cocaine, ecstasy and marijuana.
Effect of illicit recreational drugs upon sleep: Cocaine, ecstasy and marijuana.







Peace!- Granny :hippy: