My understanding is that there are very few cannabinoid receptors in the central nervous system, so it really is pretty much impossible to "overdose" in the opiate/barbituate sense.

If by "overdose" you mean take enough to have an extremely unpleasant experience where you THINK you're dying, yes, you CAN do that, & the usual culprit is edibles.

The vast bulk of my consumption is oral (tincture) & I've never gotten "too stoned." I've been where I could see "too stoned" pretty clearly, though - yep, there it is, right over there...
grumio Reviewed by grumio on . How can I effectively consume MJ without smoking it? Please help. I'm trying to accumulate a complete list of alternatives to smoking marijuana -- with kids and general public around, smoking is not an easy option. These are the ways I know of: 1. Smoking 2. Brownies (or space cakes) - however, baking these are an issue for me too. 3. Vaporization 4. Mixed with brandy or rum (warmed?) 5. Mixed with boiling milk? I've recently heard of "strips" (kind of like Listerine breath freshening strips: http://www.lovemarks.com/media/image...trips_html.jpg). Rating: 5