ok i've seen this term quite a bit on this board lately so what is 5htp?
5HTP or 5-hydroxytryptophan is a direct precurson to the neurotransmitter serotonin which is important for mood and such things as appetite. (Lack of serotonin can be responsible for depression)
This is converted to serotonin in the body and some of it passes the blood brain barrier.
Cannabinoids to interact with serotonin and 5ht receptors in some way but the details are unkown. Search google for 'serotonin tetrahydrocannabinol' or 'hydroxytryptamine cannabinoids' and you will get many results.