Hey Rusty...I know some strains will have different levels of psychoactive cannabinoids...THC, THCV, CBD, CBN...there are many others as well. With varying levels of each cannabinoid, different effects will result...If you made a long Island Ice tea with double vodka instead of tequila, may get a different buzz...Maybe that was a shitty example, but your smart enough to get my gist...
Some Indicas will put me on my ass asleep, while others will mellow out my anxiety, help relax my body, helping with my back pain, and not put me to sleep...
Not sure if this helped at ALL...lol, but I tried
whiskeytango