No Guy, Theres no way you can Contaminate it like that but removing or changing the caps is not good because if you spill QF in the threads or cap it will dry and flake off when you reopen the bottle and that can contaminate QF with flakes. I believe after heating and shaking they will dissolve but I'm not sure on that.

Just make sure it's QF, 4.0 or 4.2 and if its 4.0 check the batch number. It needs end in 06 or higher and that is located on the top left of the piece of paper with the directions inside the box. 03 thru 05 are old and can be exchanged for free at Spectrum Labs. They will work, but should be exchanged.