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07-19-2008, 08:12 PM #3
Senior Member
Cannabis-based salve experiments
Stink here are some skin penetrators that anyone can obtain. No where near the penetration ability of DMSO but these are a good second place for items that are easy for others to obtain:
a. Organic carriers- aloe vera, while aloe vera gel is effective, the use of pure liquid aloe vera is better and thus recommended. This carrier also hydrates the skin
b. Menthol either diluted (see oil list below) or in a cream base like Aspercreme (1%menthol) or Bengay (16%menthol) (which may itself have some localized effects- aspirin has been shown to inhibit oxidative phosphoralation) salicylic acid (aspirin is also a penetration enhancer). This category includes peppermint (50% l-menthol), wintergreen(50-70%) and spearmint oils(50-70%)- all of which are excellent carriers and penetration enhancers- if using oils be sure to dilute about 8 parts water or aloe vera to 1 part oil.
c. Capsicum- contained in several cream products (the more capsicum the better)- will increase absorption
d. Alcohol- that's right plain alcohol
e. isopropyl myristate- a widely available, cheap, cosmetic ingredient ...
I would probably use a combination of peppermint, aloe vera (in place of water) and a touch plain alcohol for my skin penetrator and then thicken it up with some lanolin and a very light oil to hold the cannabinoids in (don't want a heavy oil that will leave you feeling greasy).
The peppermint should give a good tingling sensation that could be slightly warming. Seems like it would be good for arthritus pain.
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