I've been over this many times but here we go again...
NATURAL does not = SAFE
SYNTHETIC does not = DANGEROUS
Nicotine and strychnine for example are naturally occuring chemicals...they are also among the deadliest of poisons, used as pesticides and nicotine even being available to the general public.

It is also important to note lsd is semi-synthetic, it has many natural precursors including ergotamine and LSA (which is several times less potent than lsd). These come from a fungus which grows on wheat and rye called ergot. The ergot contains several alkaloids, many of them highly toxic. LSD however is not toxic, there is no danger of injury or overdose from ingestion of LSD.
The effects very widely depending on set, setting and individual reaction.
You don't want do use it, thats up to you...but its not logical to 'boo' any drug if you don't have any actual input as to why it should be 'booed'.
No drug is inherently evil.