i would have to stick by Gandalf's opinion. EVERY generation since Jesus has "seen" the signs of the end times in their lifetime. I wouldn't expect this generation to be any different.

Just like we survived Y2K and the "probable" 2 millennial return of Jesus, i am sure we will be just fine after 2012. I think they are of similar threat... meaning none at all.

I would be more scared about the day when man creates artificial intelligence that is "smarter" than us making us no longer the most developed form of consciousness on the planet. This might very well be a possibility over the next 40 years with the current rate of technological advancements. Things could get hairy then. You can read more about it by googling "technology singularity." Yes, this is just a theory too, but at least it is based on observable facts and numbers of today as opposed to coming from an ancient religious text or beliefs with doubtful authenticity.