Short answer...No, there is no reason to have your plant upside down.

But as was mentioned before, the slower the dry, the smoother the smoke.
Fencewalker Reviewed by Fencewalker on . little help pls... it is necesary to hang the plant down to dry it?, my skunk gave up really... i didnt put the correct fertilizer or something,,, and they gave up badly.... so i ll remove them of my tent... Can i grind the "smokeable" thinks of the plant and let it dry, just like that, could i? Rating: 5