Insufflation of ANY drug could result an irreversible damage to your septum...there are other routes of administration, oral, rectal, intra-muscular or how about just occassional insufflation which shouldn't do much lasting damage to your nose? You can even get creative...make a solution with ketamine in a spray bottle, adjust your dosage and you can spray it right up your nose.

but u no what...who really cares....id probly try k once or twice to see whats it like...ya dxm isnt healthy for u but its better then sum of that shit out there (e, meth)
I disagree there, real ecstasy (MDMA) is relatively safe when used responsibly as is dxm, ketamine and even amphetamines. Im sure you must have heard ecstasy is neurotoxic and seen those bullshit images, those do not show brain damage...they show the amount of serotonin in your brain which will be low considering MDMAs effects come from the rapid release of this neuro transmitter. This is only temporary and your brain will return to normal in a couple weeks maximum. 5HTP supplements can be taken afterwards to increase the levels of serotonin in your brain. Prozac and other SSRIs can be taken following rolls to prevent any neurotoxicity. The issue of MDMA neurotoxicity is still controversal as George Ricaurte, the man who supposedly proved MDMA killed brain cells in primates, and his research team at John Hopkins university fucked the experiment up...they gave the primates methamphetamine, not MDMA.
http://www.dancesafe.org/slideshow/
http://dancesafe.org/documents/druginfo/risk.php