Am on zoloft right now it is 15mg people go up to 300-400mg a day. Cannabis can defenetliy help with deppression or anxiety. But if you have imbalanced chemicals in your brain than zoloft will make them balanced even tho you might not like the side effect of the drug. Thing is you can take the anti and not be happy. And than ones you are done taking it you your deppression might stop. Am in the same situation as you. But am always open to everything. My doctor told if i don't like the meds i can stop taking them. If you really dislike zoloft you can tell your doctor and they will try diffrent meds. All am telling you is that moving out to california and smoking weed everyday for your depression could work. But not if the chemicals in your brain unbalanced. Weed can't balance them. It raised them once you are high but the go back to the way they were. So keep your options open. :jointsmile: