You should not smoke weed with any antidepressant medication. Just try out the meds alone first. Give it 2 weeks and then you c how you feel. You can start smoking after you give it atleast 2 weeks. You don't have to but weed works on serotinin just like zoloft so when you mix you don't know really know what is doing what. So try ethier just taking the meds or only smoke a little bit and not everyday. You can't really expect changes to happen really soon everything requires time my friend. Just be patient and you will find what is right for you.