Yes, that's the concept behind aeroponics. Some systems sold as 'aero' are kinda coarse sprayers, but the finer the fog, the more effective it's going to be. You'll want to poke around and see what nutes people like to use in their aero setups.

Since you are OBVIOUSLY talking about legal culinary mushrooms I'll leave your first post up.. you ARE, correct? Mmm shiitakes...