2 4 light rooms so that your electric draw and heat load in the house are constant.
And never discuss a commercial grow, especially one where you are renting a whole house for it, on the internet.
Do you have a source of female clones? If not, you WILL need a third room to house mothers and cuttings.
What size lights in the flower rooms? 36-49 plants under each HPS-1000, flowered as recently rooted cuttings with 1-3 weeks' veg time, in gallon pots in SOG, is the most efficient.
If you are running 600s, 25 or 36 plants per light.