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02-07-2008, 12:26 AM #1OPJunior Member
Dilution: Possibly interesting data.
Hello all. First my own story and then the data. I've now abstained for 23 days and am still failing using my first mornings void. I'm 6 foot, 190 pounds, medium build. While usually only a weekend smoker, I lost my job in early December and smoked heavily for about 5 weeks. I have a drug test in two days (for my new job) and am going to need to dilute my urine. While reviewing the information posted on this board, I came across a study performed by the DOT.
Summary: 56 subjects were water-loaded to determine if water-loading can result in failing a test for 'substitution'. (They found water-loading could not result in 'substitution' failure). Each subject was required to drink 80 oz. of liquid over a 6 hour period. Urine samples were collected the morning of the test, prior to the test, every hour during the test, and the following morning of the test. 113 of the 500 urine samples would have been labeled as 'dilute'. If we assume none of the morning samples and prior test samples were found to be dilute 113 of 336 samples were found to be dilute. Conclusion: Eat your rolaids, drink your gatorade, and eat your red meat or there is a very likely chance your specimen will be found dilute.
Thanks for everyone who has contributed to this topic, and I'm sorry if this has already been discussed.
You can find the entire report in the url below, page 19.
http://www.dot.gov/ost/dapc/frpubs/F..._Part%2040.pdf
I've copied and pasted the relevent info below.
To provide further information about
these issues, the Department conducted
its own study. The text of this study is
available on the ODAPC web site
(U.S. Department of Transportation/ Office of the Secretary of Transportation/ Office of Drug & Alcohol Policy & Compliance). The study was
designed specifically to focus on two
issues on which commenters criticized
the HHS literature review, the absence
of paired studies and insufficient study
of female subjects. The DOT study made
paired measurements of urine creatinine
and specific gravity in a predominately
female (40 of 56) group of subjects.
All participants in the study were of
reasonable working age (19â??56). All
participants volunteered to consume at
least 80 ounces of fluid spread evenly
over six consecutive hours. The protocol
asked for 40 ounces to be consumed
within the first three hours of this sixhour
test period. This would be
immediately followed by the
consumption of at least another 40
ounces in the last three hours of the sixhour
test period. Urine specimens were
collected prior to the start of the sixhour
period and at the end of each
subsequent hour in the test period.
Urine specimens were also collected on
awakening the morning of the test day
and on awakening the morning
following the test day (this amounted to
a total of nine urine specimens being
requested from each participant).
Each participant was asked to
document the amount and type (water,
coffee) of fluid consumed from
awakening through completion of the
six-hour period, along with the total
amount of urine produced from
awakening through the six-hour period.
Height, weight, age, gender, ethnicity,
eating habits, and medications taken
regularly and on the day of the
collections were also documented. All
urine specimens were sent to an HHScertified
laboratory where creatinine
and specific gravity were measured
using well-established laboratory
techniques.
The 56 subjects provided a total of
500 urine specimens. 504 specimens
were expected; however, three
individuals did not collect one of the
specimens on awakening, and one
person was unable to complete the
second three hours of drinking per the
test protocol. Two participants were
unable to consume the minimum
amount of fluid originally intended
(total of 80 ounces, or approximately
2370 mL, spread evenly over the six
hours). The remainder consumed at
least the minimum requested. Twelve
participants (five men and seven
women) consumed over one gallon of
fluid by the end of their test periods.
Not one of the 500 specimens was
identified as â??â??substitutedâ??â?? based on the
HHS criteria. This point deserves
emphasis. The DOT research involved
paired studies of predominately female
subjects who drank copious quantities
of water under controlled conditions.
This examination of paired values of
creatinine and specific gravity from 500
specimens collected under water
loading conditions strongly supports the
criteria developed by HHS. There was
no evidence that individuals, regardless
of gender or other factors and despite
consuming unusually large amounts of
fluids, are capable of physiologically
producing urine meeting the HHS
substitution criteria. We do note that
113 of the specimens did meet the
criteria for â??â??diluteâ??â?? specimens, as
defined by HHS. Under Part 40, a dilute
specimen does not constitute a refusal
to test.michwmichw Reviewed by michwmichw on . Dilution: Possibly interesting data. Hello all. First my own story and then the data. I've now abstained for 23 days and am still failing using my first mornings void. I'm 6 foot, 190 pounds, medium build. While usually only a weekend smoker, I lost my job in early December and smoked heavily for about 5 weeks. I have a drug test in two days (for my new job) and am going to need to dilute my urine. While reviewing the information posted on this board, I came across a study performed by the DOT. Summary: 56 subjects Rating: 5
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02-07-2008, 02:48 AM #2Senior Member
Dilution: Possibly interesting data.
Good post. I've seen it before. So according to dot's own testing you can drink 40 ounces of fluids every 3 hours for as long as you want and about a third will come back with anegative dillute. So like you say Eat your rolaids, drink your gatorade, and eat your red meat and you it should really help. I know in my own testing it has helped.
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02-07-2008, 09:37 PM #3OPJunior Member
Dilution: Possibly interesting data.
I had my dry-run today. First mornings void showed the faintest of lines if one squinted.
I ran through the recommended diluting process as outlined in the sticky, with the exception of drinking 32 oz. of gatorade rather than 48 oz. I'm very concerned with the stigma attached with returning a negative-dilute sample, and figured since I had abstained for 24 days now, I wouldn't need to dilute to the fullest extent. My semi-diluted test showed a very strong line! I wasn't thrilled with the color of the urine, green-yellow rather than brown-yellow, so I'll probably only take one B-complex vitamin tomorrow rather than two.
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02-07-2008, 10:13 PM #4Senior Member
Dilution: Possibly interesting data.
Sounds like you got it down.You should pass no problem
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02-13-2008, 01:09 AM #5OPJunior Member
Dilution: Possibly interesting data.
I Passed. Just received confirmation today. Back to work on Thursday, and back to smoking this weekend!
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02-13-2008, 03:24 AM #6Senior Member
Dilution: Possibly interesting data.
Originally Posted by michwmichw
Signature? I Don\'t Need No Stinkin Signature !!
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