Tubing can be a tight fit on the glass, especially after it's been on awhile. Put your whip (where the glass/tubing connection is) in boiling water for about 5-10 seconds. This will make the tubing more pliable and easy to wiggle off the glass. You can even leave the glass in the boiling water for cleaning, although you may have to clean with ISO to do a complete job. The tubing can be used for quite a while without cleaning although you could run hot water through it if you want. I wouldn't use ISO or other cleaners on it, unless it's a green cleaner. You can buy new tubing from VB or some place like US Plastics. Just look for food grade tubing.