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My understanding is that while increased water consumption doesn't alter glomerular filtration rate, it does affect biliary excretion - although I can't defend that mechanistically or with any study that compares high water load serum levels with low water load levels.
What are you saying, that high levels of water affect biliary excretion of THC metabolites. I don't think it does and I'm not talking about the difference between being dehydrated and having normal fluid volume. Whenever I talk about excess fluids I am comparing it to someone who is at normal fluids volumes, not someone already dehydrated or hypovolemic, and someone who is force feeding themselves fluids. Again, your body must maintain water homeostasis or you get osmotic shifts or you'll die so your body decreases ADH production, decrease in production of aldosterone, etc etc etc. So while your taking in all that water your body is pulling water from the blood. I might be wrong but I don't think so and I'm going to ask a gastroenterologist friend of mine but I don't think increased fluid intake in someone who is hydrated is going to affect bile excretion, biliary excretion of THC metabolites, hepatic function or hepatic elimination of THC metabolites.
Soluble fiber on the other hand does play a role in all of this. You can search my posts on this.
Originally Posted by cosmas
Probably about 80 percent of THC is excreted in stool, so, if true, increasing that pathway would be beneficial.
It's more like 60% fecal 40 % urine.
Originally Posted by cosmas
And drinking water, while not changing GFR, does dilute urine. Double the milliliters and you effectively half the measured nanograms. I would stick with the water drinking.
I never said dilution didn't work. I am quite familiar with dilution. What I said was:
Originally Posted by FakeBoobsRule
It is good to stay well hydrated but over doing it the day before the test isn't going to increase GFR.