hot boxing a room might do it, but it's still unlikely, because of the density you need to reach. The detector is looking for particles in the air larger than those in the smoke you're creating. In such a situation where you would be hotboxing anything, it is likely that you do not need to worry about someone being suspicious that the smoke detector was taken down, and so can just remove it temporarily. For that matter, covering them with socks works well too (I have the hard-wired 120V type in my trailer and they go off every time I use the oven). Assuming the alarm is in reach, just do your hotbox. If it goes off you can quickly cover it or take it down. You're supposed to play it safe with smoking since it's easy to start a real fire with the things you are smoking (butt falls out of an ashtray). So better not to defeat the alarm unless it actually does go off false. But in many years of smoking weed and tobacco, and with all the relatives over the years who smoke cigarettes, I've never heard of this type of smoke setting off an alarm.