what type of painkillers are you talking about? Sounds like you have been taking codeine, vicodin or something similar. MiraLAX works very good and it is very mild but works like a son of a bitch ...you mix it in with anything you drink such as juice or whatever and in a couple of hours your good to go...:thumbsup:, or you can go with a FLEETS enema for instant relief..either way you gotta get them pipes cleaned out. Good luck