It depends on how much weed I have. If I know that I'm going to be conserving a quarter or something, I'll try to use my pipe everytime I smoke, and let the resin build up, so that I can scrape and smoke it to make my wait until my next bag a little more tolerable.

When I decide to clean it, I scrape the resin off, and smoke it. And then after I decide that the rest of the filth is in the stem, I'll either boil it or put it in some really hot water and let it soak. After I think everything is loosened up enough, I let the nasty brown liquid drain out and then let it dry on a towel. Usually dries within like 5-10 minutes, and then I use it again .