Um.... Beachguy, the article's appreciated and all, but what did that have to do with anything relating to this thread?:wtf:
Gandalf_The_Grey Reviewed by Gandalf_The_Grey on . Wondering about a particular effect of THC on the MU1 receptor-agonist mechanisms Last night I was in a significantly extra large amount pain so I took an extra dose of tramadol (a morphine receptor agonist), and now I've woken up at 3:00am with seratonin blasting through my brain. I'm unable to sleep because my brain is utterly excited, eccentric and wildly creative in thought, enthusiastic and possitive in outlook (as opposed to the usual as of late), and overal very clear thinking. I attribute this to the increase and reuptake-inhibition of seratonin triggered by tramadol Rating: 5