rhizome, thanks for responding.

OP- when you say the soil is "old", what do you mean? Has it been previously used? If so, what was the previous cultivar? It was not previously used. It just seems old and crusty. The perlite on top is turning brown. 2 plants shared this container, but one was pulled after 2 months because it turned out to be male. That was maybe a year ago. It's probably fine; it's just the hydro farmer in me wanting everthing to be changed out occaisionally.

Do you, or does anybody else in the dwelling, smoke tobacco? No, and it's a new home.

Have you had any whitefly or aphid issues? No, Never.

How quickly is this progressing? Days, weeks,...? More like weeks. Notice the top growth doesn't have it, but it is all twisted for weeks after emerging. It seems like maybe 3 weeks after emerging the leaves start getting mottled, and die a month or so after that, but they are brittle from the start. This plant has always grown reeeal slow.

Are there any cankers where petitole meets meristem? No, I tried to pry back the thick underbrush for a photo of this (first photo).

How old is this mom? A year plus a little, maybe 2 or 3 months. It's been doing this for several months, but not so bad as of recent.

When was the last time she was trimmed? Never, except for completly brown leaves. Never revegged either.

I would quarantine that plant. Even if it's not pest related?

Would it be possible to get a shot of the underside of an effected leaf? Yes, quite possible. Except for the first one, all photos are of the underside of leaves. The second one is a side by side of two leaves, one of which doesn't look nearly as bad from underneith, but looks about the same on top. Weird, huh? The leaf on the right is from about 4 inches from the top, and the left one is about 1.5 inches lower. The last picture is of a leaf in it's last stages, just before turning completely brown.