I notice the difference between my mic'ed bud and my non-mic'ed bud. I mic about 3/4 of my bud, and leave the other 1/4O alone just so I can enjoy the original taste and high from the stuff, and the difference is notable for sure.

It works best with lower grade weed, as the properly cured high quality stuff has already done the majority of the THCA -> THC conversion. I can take low end mids and get wrecked out of my mind on a single bowl, when it normally takes me 5-6 bowls to get that high. But high end stuff just seems slightly different, not alot, but noticable because the high changes slightly.

And we ruled out the placebo effect in my apartment because we would take turns with bowl packing on putting in mic'ed or non-mic'ed weed without letting the others know which it is, and seeing if the others noticed or got higher, and without fail every time, they were able to tell if it was mic'ed or not.