I give great credence to evolutionary biology and anthropology. We have evolved with cannabis and, to a much greater extent, alcohol. However, we have not evolved with many modern stresses and most prescription medications. I also believe that "modern medicine" is highly overrated, and not nearly as advanced as many people would like to think. We have a good understanding of most organ systems and so forth, but relatively very little understanding of the brain and mind. Taking mind-altering prescription medicines may certainly help, but they surely are no substitute for actively, naturally coping with the causes of stress. Stress and pain are there for a reason, and in terms of evolutionary biology, those feelings are not there to tell you to take a pill.