Although U2 maybe annoying, you can't deny the longevity they've enjoyed. They're still together with original members and original Manager. They've won 22 Grammy's, more than any other rock band. I can totally see how a lot of their music wouldn't appeal to people as a lot of it is overplayed and some of it , never played.
For me though, it'd be Staind,Linkin Park and Alanis Morissette... They give my ears pain.