nah main, you get a tolerance to one strain you change strains and bamn it is close to imposible to build such a high tolerance that you can not get to that sweet spot, I knows people in Amsterdam that cary around about 10 different mind blasting strains to smoke in one day indca in the morning then hybrids all day till evening then Sativas or heavey Sativa hybrids, They have an unlimited amount and more strains than you could ever smoke in 6 months, Just change your strain main