I never took meds for depression - I didn't like the concept of it - so I can't really help you out here. Smoking weed has helped a lot though. The euphoria is a temporary thing, but being able to step back from life and take an objective look at what I was doing and how I acted was the most valuable part of it. Off-topic.

Try it once, take it slow, and if you don't have a problem then keep going if you want. It won't mess you up permanently, if that's what you're wondering.