well for shrooms it would be REALLY fast, you build a tolerence immediatly. For most people if you dose one day then dose again the next day the second time you would have to take double what you took the first time. Im not sure how fast the tollerance for Lucy builds but there is a cross tolerence. For example if you dosed on shrooms one day then did Lucy the next it wouldnt be nearly as good if you waited like a week.