Quote Originally Posted by birdgirl73

My theory is that it must have something to do with the gradual desensitization of cannabinoid receptors that occurs. Or possibly, too, with its action as an early vaso-constrictor, followed by vaso-dilation, which might trigger spasms in some of your nerve pathways, worsening the inflammation (same mechanism by which it triggers headaches in some people). As you got more cannabis exposure, your body became less sensitive to it, and yet it still sent some of those vessels and nerves into spasms. This is just a guess, and it's not a very educated one.
Oh yes, I forgot to respond to this part. While I know this is just a guess, you may have something there, albeit I don't understand how vasco dilation/constriction causes "spasms" in nerve pathways ( I didnt' know nerve pathways could spasm). The reason, though, that I think you have something here is because when I get high and the pain worsens I can feel this sort of "tension". There's absolutely no muscle tension, in fact it's reduced, but it's like a tense energy that's flowing through my body at the core. Similar to caffein high actually, which is also a central nervous system stimulant.

Furthermore, when I take Tramadol which is central nervous system stimulant, it seems to greatly reduce if not altogether eliminate this tense energy. If anybody's wondering how something that makes many tried can be a CNS, it's because it's also an adrenal gland suppresant. Personally though, it just makes me energetic and happy (and for some rason extremely irritable if you rub me even slightly the wrong way:wtf