it usually takes an hour forty five to two hours for them to kick in. i make 'em with about a joints worth per cracker, putting the finely chopped bud between layers of peanut butter. for extra delay, put a dab of real butter on the bud before you close up the stumble cookie. after one hour and forty five minutes of ingesting two of these babies, eat something sweet like chocolate chip cookies or a cupcake. all of a sudden your mouth will go dry and you will say "whoa!"