For me, 2 weeks has a small difference, but in the end it's not much. Personally, if you're just breaking to get a real good high again, I'd say go for 4 days or so and smoke again. And also from my experience, when I take a break and smoke the first time, the following times are still somewhat better than is normal with lots of tolerance. I've found after a week or two (depending on how much I'm smoking) my tolerance will go back to normal levels. Hope that helps.