It last for about 4 hrs. I felt a little upset but that went away again everyone is different. And something I forgot to mention in my story. I felt very itchy, but when I scarth my skin it hurt to itch it. It was just the drug on my brain though. Other than feeling sorta sick and me THINKING I felt pain when itching my skin. Nothing else. But then again some people have reported puking their guts out drinking this stuff