Forgive the snark, but I believe Hillary's problems stem from several root causes:
A) She didn't find Jesus at the bottom of a bag of coke
B) She hasn't mishandled damn near every responsibility ever placed in front of her, from an oil company down the tubes to hiding while a U.S. city was almost wiped off the face of the earth to getting US caught in the biggest Grecko Roman Cluster Fuck in recent memory.
C) God doesn't speak to her personally*
BBC - Press Office - George Bush on Elusive Peace
D) Even with interns on their knees, the Clinton's favor work over lazines. People don't like work, they like vacations. Thats why Shrub's constent vacations back to Texas helps fight Terror. By 2005, 20% of The Decider's presidency had been spent on Vacation. Vacationing Bush Poised to Set a Record I seem to remember this being a major problem in the lead up to 9/11

More to come...