Question of the Day: Is THC Water Soluble?

I found this at overgrow.com.

kaljukajakas || title:|| ||author:kaljukajakas|| ||forum:8||
Normal dextrin is easy to make at home (heat starch in an oven), cyclodextrins are made using special enzymes or bacteria. I doubt they're are used much for generic applications... But if you want to experiment you could start with something as simple as sugar or glucose to enhance the water solubility of THC: like dissolves like (water is very polar, syrup is less so). Adding surfactants would be the easiest way but I doubt anyone wants foam in their lungs ;)

Dissolving the THC in a bit of alcohol before mixing it with a cyclodextrin solution would be a good idea. Better still, make a concentrated 2:1 cyclodextrin to THC solution in alcohol and then add water. Cyclodextrins might be too insoluble in alcohol though for this to be practical. Additives stabilize a solution, getting stuff to dissolve in the first place is the difficult bit. Shaking a blob of honey oil to get it to dissolve will, of course, take forever.

I doubt this approach will be easy to implement. :( Beta-cyclodextrins (best suited for THC-like molecules) are not very soluble and since at most one cyclodextrin molecule will complex with one THC molecule the amount of water to be inhaled might be too great. But perhaps you could coax a THC molecule or two into a gamma-cyclodextrin ring. That might work, but this really is too complex stuff for speculation. God knows what the formation constants are...

Weird, I distinctly remember reading somewhere that the solubility of THC is ~100mg/100cc not ~0.1mg as it actually is. :confused:

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Tetrahydrocannabinol (THC)
Chemical name (-)-(6aR,10aR)-6,6,9-trimethyl-
3-pentyl-6a,7,8,10a-tetrahydro-
6H-benzo[c]chromen-1-ol
Chemical formula C21H30O2
Molecular mass 314.46 g/mol
Boiling point 200 °C
Solubility 2.8 g/l (water, 23 °C)
CAS number 1972-08-3

Erm... that would be too long and complicated to read.

But thanks :D

so is THC water soluble?

No, i'm pretty sure it's not.

No. The above article appears to be about increasing the water solubility of THC. The reason for this is that low solubility of THC in water hinders its applications as a pharmaceutical.
For example if one wanted to inject THC for any reason it would have to be made soluble in water.
http://www.ncbi.nlm.nih.gov/entrez/q...&dopt=Abstract

It is somewhat soluble.

Drinking bong water will produce minimal psychoactive effect, since THC and other cannabinoids are minimally soluble in water. -Wikipedia

Quote:

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Originally Posted by beachguy in thongs

It is somewhat soluble.

Drinking bong water will produce minimal psychoactive effect, since THC and other cannabinoids are minimally soluble in water. -Wikipedia

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Unless it's just a placebo, and the Wikipedia people are gullible :p

Well I wouldnt suggest drinking bong water.
But thc is water soluable in small amounts. Small enough that it is generally not a recommended method of extraction/consumption. It depends on your desired results. Many drink tea for pain, nausea and insomnia.
Remember there are upwards of 60 other cannabinoids in pot so each contributes to the effects you feel when you drink steeped pot tea, or ingest butter, or smoke it.
Most of the talk is about thc but it is one contributing factor to your high or med value.
Cannabinoids are more readily soluable in fats so butter is always a favorite for extracting a large majority of active ingredients from even the crappiest of weed.
This article is more referring to how to prepare a solution to enhance the eventual water solution which isnt really an appeal to anyone looking to ingest.
I would say that using an enhanced water extraction for smoking oils would be a longer process since the eventual evaporation part of the job is going to be lengthy. Water evaporates at a much slower rate to conventional solvents.
Either way ita amazing what science can figure out :stoned:

i would have simply said yo beachnigga, THC isn't water soluable. but it's alright, mang. people find shit out on their own, and sometimes it's a lot better that way. :pimp:

Quote:

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Originally Posted by dustoned

i would have simply said yo beachnigga, THC isn't water soluable. but it's alright, mang. people find shit out on their own, and sometimes it's a lot better that way. :pimp:

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You tryin'a kill him?!

Lol :p