My Experience with Rick Simpson Oil

These are all great questions. There are some that I simply cannot answer. However, I believe that many of your questions can be answered here.

Phoenix Tears

Also, here is another video of a miracle cure with a type of cannabis oil that I recommend to view. Shona Banda wrote a book "Live Free or Die", she talks about her battle with crohn's disease. Shona talks about Simpson oil and I heard she speaks of the red oil in her book. I have not read the book yet so I cannot confirm.

Shona Banda - Live Free or Die - YouTube

I recalled reading about the Ispropyl issue some time ago. It's been sticking in my head so today I did a bit of digging on a different board and came up with some information written by Oldmac who taught me a GREAT deal, both directly and via his writings to others in various forums and boards. He was an AWESOME mentor. I have not seen him online for some time. OM I hope you are OK. We miss you!

Anyway, OM recommends using grain alcohol. I see the logic and it is the route I will go if I ever go down this road. I hope this adds to the knowledge base here and the discussion!

Quote:

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Originally Posted by Oldmac

By law each 100ml of "denatured" alcohol must contain no less the 355mg of sucrose octaacetate and no less then 1.4mg denatonium benzoate. These, especially denatonium are also added to anti-freeze, windshield wiper fluid etc. to keep people, kids and animals from ingesting such items. But signifacant amounts remain after denatured alcohol evaporates and even tho both are benign if ingested orally, the burning of denatonium benzoate has been shown to be a carcinogen.

Since I have spent the last 25+ years providing mj to cancer treatment patients and also hospice care patients (I see many from the first group later in the second group) I find that anything that falls into the carcinogen category offensive. Especially so when cause (exposure) to effect (cancer) can be 10, 20 or 30 years later.

If you want to take the chance...fine by me, but I would appreciate it if you did not pass along such a recipe to others. Especially since an alternative, grain alcohol, is available.

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I have seen this debate before and I have found through my research that there are many pros and cons to many solvents.

For example 190 Everclear has 5% water in it, which can extract the red oil from the plant material. If you are using chemical fertilizers, you will also be extracting that which in turn will end up in the finished product due to the fact that the fertilizers are water soluble, where the THC and other elements are oil soluble.

I stick with the fact that the quality of the cannabis and the quality of the method of converting into the oil, everything else is secondary. Also, all the people I have seen debate on many, many posts and sites, not once have I seen one of the people try both ways and do a quality comparison. In the future I myself would like to compare iso with 190 everclear. I forewarn, anything less than 190 everclear, it is a wast of money and time, in my opinion.

I have also read that comparing the toxins in the liquor or iso that the liquor carries half the toxins as the iso, so if I am not mistaken, it is probable that the remains of the liquor after processing the oil may also carry a percentage of carcinogens similar to the iso.

I agree, it is worthy to try. Thus far I have no reason to believe that the iso is more dangerous.

Now if he is talking grain alcohol like "moonshine", I have read that it cannot be used, that it is far more dangerous in many ways, I just can't remember the details.

Howzit Bigs.

The problem with that logic, is the confusion of denatured Ethanol with Isopropyl alcohol.
One of the few thing Oldmac ever got wrong.

Denatured Ethanol does indeed contain those denaturants and should never be used for tinctures, or extractions.
Un-denatured, ethanol, (Grain alcohol), is very expensive and I found it to be less efficient than I. A..


Isopropyl alcohol does not need, and does not contain, any denaturant
It is not necessary.

The skinny:
"
PHARMACOLOGY AND TOXICOLOGY
Isopropyl alcohol is a sedative-hypnotic agent whose toxicity closely resembles that of ethanol, with which it shares strong structural similarity. Like ethanol, isopropyl alcohol's precise mechanism of action in the central nervous system (CNS) remains uncertain. Changes in membrane fluidity and/or function, and interactions with neurotransmitter receptors, are believed to account for the CNS effects of alcohols and other simple hydrocarbons. There is a linear relationship between the molecular weight of alcohols and their sedative effects: as size increases so does sedation. Thus, isopropyl alcohol is marginally more potent than ethanol at comparable concentrations.

Fatality from isolated isopropyl alcohol toxicity is rare, but can result from injury due to inebriant effects, such as untreated coma with airway compromise, or rarely, cardiovascular depression and shock following massive ingestion. Supportive care can avert most morbidity and mortality. It is important to differentiate isopropyl alcohol poisoning from methanol and ethylene glycol, which are more dangerous. Isopropyl alcohol does NOT cause an elevated anion gap acidosis, retinal toxicity (as does methanol), or renal failure (as does ethylene glycol).

In untreated animals, the median lethal dose lies between 4 and 8 g/kg. Many sources estimate the lethal dose to be 250 mL in humans (eg, less than 400 mL of a 70 percent solution). It is important to recognize that, with treatment, adults and children have survived much larger ingestions.
"


Isopropyl will cause serious gastric disturbance if ingested.
(They still get idiots in the E. R. that try it.)
However, it does evaporate completely, leaves no residue, and is quite safe for oil extraction.

Last time O.M logged in to a sister board was 10/25/11. He left no message.
Old fart's got me worried.

Aloha,
Weeze

Quote:

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Originally Posted by Weezard

Howzit Bigs.

The problem with that logic, is the confusion of denatured Ethanol with Isopropyl alcohol.
One of the few thing Oldmac ever got wrong.

Denatured Ethanol does indeed contain those denaturants and should never be used for tinctures, or extractions.
Un-denatured, ethanol, (Grain alcohol), is very expensive and I found it to be less efficient than I. A..


Isopropyl alcohol does not need, and does not contain, any denaturant
It is not necessary.

The skinny:
"
PHARMACOLOGY AND TOXICOLOGY
Isopropyl alcohol is a sedative-hypnotic agent whose toxicity closely resembles that of ethanol, with which it shares strong structural similarity. Like ethanol, isopropyl alcohol's precise mechanism of action in the central nervous system (CNS) remains uncertain. Changes in membrane fluidity and/or function, and interactions with neurotransmitter receptors, are believed to account for the CNS effects of alcohols and other simple hydrocarbons. There is a linear relationship between the molecular weight of alcohols and their sedative effects: as size increases so does sedation. Thus, isopropyl alcohol is marginally more potent than ethanol at comparable concentrations.

Fatality from isolated isopropyl alcohol toxicity is rare, but can result from injury due to inebriant effects, such as untreated coma with airway compromise, or rarely, cardiovascular depression and shock following massive ingestion. Supportive care can avert most morbidity and mortality. It is important to differentiate isopropyl alcohol poisoning from methanol and ethylene glycol, which are more dangerous. Isopropyl alcohol does NOT cause an elevated anion gap acidosis, retinal toxicity (as does methanol), or renal failure (as does ethylene glycol).

In untreated animals, the median lethal dose lies between 4 and 8 g/kg. Many sources estimate the lethal dose to be 250 mL in humans (eg, less than 400 mL of a 70 percent solution). It is important to recognize that, with treatment, adults and children have survived much larger ingestions.
"


Isopropyl will cause serious gastric disturbance if ingested.
(They still get idiots in the E. R. that try it.)
However, it does evaporate completely, leaves no residue, and is quite safe for oil extraction.

Last time O.M logged in to a sister board was 10/25/11. He left no message.
Old fart's got me worried.

Aloha,
Weeze

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Why thank you.

I am not qualified to properly debate on which methods of extraction are better or more safe. I do know that the 190 Everclear will not extract as much TCH as the 99% iso, and the end product (oil) will be more diluted.

I put my trust in Rick Simpson. He is more qualified than I am regarding methods of extraction. He mentions that the iso is a safe alternative to other solvents, so that is what I chose. From a cancer patient's view, like my patient, the iso method has already been proven to work. Using anything else that could cause the oil to come out more diluted would reduce my confidence in its effectiveness.

Bottom line, the most important thing here is that more qualified medical marijuana patients having the opportunity to get safe access to high quality cannabis oil. Also, for everyone in the medical marijuana community to be educated on the potential medicinal benefits of the oil.

Hey Weez, thanks for setting the record straight. I appreciate you taking the time to lay it out so concisely. I'm quite interested in the subject. And like anything we do, more learning is always a good thing. Hope you are well.

And thank you, G.G.!

This is an excellent thread!

Were it allowed, I'd rep you daily for it.

I know a li'l chemistry, a li'l electronics, some physics, medicine, dat kine sing.
Anyway that I can he'p, be not shy.

Aloha nui,
Weeze

Quote:

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Originally Posted by bigsby

Hey Weez, thanks for setting the record straight. I appreciate you taking the time to lay it out so concisely. I'm quite interested in the subject. And like anything we do, more learning is always a good thing. Hope you are well.

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I try my 'umble best. :-}

Thanks for the concern.
If my home-brew oil is up to snuff, I'll be quite well.

Howzit with you, brah?

Weeze

GrowGoddess, thank you so much for sharing this information. Read a post on a different site of someone who put a years worth of AVB in a blender with 99%ISO and let it run for 10 minutes, Then strained, let the alcohol evaporate, and made candies with the remaining goo. Similarly I soaked a 1/2 oz of mexi-brick weed in 5 ozs of Everclear for 5 months, strained, let it dry and ended up with maybe a gram and a half of blackish/greenish hash like goo that was quite potent considering it's humble origins, which were worthless to smoke. I suspect that if either conconction were attempted with quality, all bud product, that the results would be of a similar nature to Rick Simpson oil. Think I'll get some 99% iso once Christmas is over.

Hi guys,

My first post here. I was trying to find perfect strain to make Rick Simpson Oil. He recommends any Indica strain that has 20% or more THC.
I have found on forums that Blueberry, LA Confidental, Buba Kush can be used to make RSO.
I did some RSO with 99% isopropyl alcohol and it's very strong. I don't know which strain I used. Didn't grow it myself.
My wife used it and she can handle only 2-3 rice grains of oil per day. It's very hard for her to increase the dosage. For sure it will take some time.
My questions are:
Are these strains OK to make RSO? Any recommendations are welcome.
Where to buy seeds? We live in Europe. Found some sites like Resin seeds, Rhino seeds, London Seeds centre, Amsterdam seeds,...
Should I buy feminised seeds?
I am planning to grow it and any suggestion on that are very welcome.
Maybe I should grow some strain which is easy to grow. I am interested in Indoor strains.

Cheers

Vac